Properly annealedlampwork glass beads are extremely durable. I've dropped them on concrete floors, run them through the washer and dryer (again and again), and otherwise abused the poor dears on a pretty constant basis with no damage to the beads.
There's a higher chance of breaking off a piece if the bead has raised decorations or is sculptural in nature as the finer points offer a weak point if dropped.
As long as you purchase annealed, artist/artisan, high-quality lampwork your beads should withstand a lot of abuse. If you purchase cheap, factory made lampwork beads from India, China, or similar there's no telling what you'll get. Be wary of sellers who sell "studio" beads and pose as artisans.